| S4637 |
Prasugrel Hydrochloride |
Prasugrel hydrochloride (Prasugrel HCl, LY640315,PCR 4099 Hydrochloride) is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome. |
Selective |
|
| S3216 |
Uridine 5'-diphosphoglucose disodium salt |
Uridine-5'-diphosphoglucose (UDPG, UDP-Glc, UDP-D-Glucose, UDP-α-D-Glucose) activates the P2Y(14) receptor, a neuroimmune system GPCR. Uridine-5'-diphosphoglucose is the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. |
Selective |
|
| S3737 |
Cangrelor Tetrasodium |
Cangrelor (AR-C69931MX) is a potent, competitive P2Y12 receptor inhibitor that is administered by intravenous infusion and rapidly achieves near complete inhibition of ADP-induced platelet aggregation. |
Selective |
|
| S4079 |
Ticagrelor |
Ticagrelor (AZD 6140, AR-C 126532XX) is the first reversibly binding oral P2Y12 receptor antagonist with Ki of 2 nM. |
Selective |
P2Y12, Ki: 2 nM |
| S2855 |
MRS 2578 |
MRS2578 is a potent P2Y6 receptor antagonist with IC50 of 37 nM, exhibits insignificant activity at P2Y1, P2Y2, P2Y4,and P2Y11 receptors. |
Selective |
P2Y6, IC50: 37 nM |
| S1415 |
Clopidogrel (SR-25990C) Bisulfate |
Clopidogrel (SR-25990C) Bisulfate is an oral, thienopyridine class antiplatelet agent. |
Selective |
|
| S1258 |
Prasugrel |
Prasugrel (Effient, Efient, Prasita,CS-747, LY640315,PCR 4099) is a thienopyridine ADP receptor (P2Y12) antagonist, used for the reduction of thrombotic cardiovascular events. |
Selective |
|
| S3293 |
Gardenoside |
Gardenoside is a natural compound extracted from Gardenia fruits, with hepatoprotective properties. Gardenoside inhibits TNF-α, IL-1β, IL-6 and NFκB activation. Gardenoside also has an inhibitory effect on free fatty acids (FFA)-induced cellular steatosis. Gardenoside suppresses the pain in rats model of chronic constriction injury by regulating the P2X3 and P2X7 receptors. |
Pan |
|
